Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides.

نویسندگان

  • Xu Zhu
  • Shunsuke Chiba
چکیده

Lewis acid-mediated conjugate addition of vinyl azides to electron-deficient alkenes led to the efficient construction of 1-pyrroline skeletons. The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3',4'-dihydrospiro[indoline-3,2'-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles.

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عنوان ژورنال:
  • Chemical communications

دوره 52 12  شماره 

صفحات  -

تاریخ انتشار 2016